Results for 'hepatic dysfunction'
Mohamed Elmeliegy PhD, Derek Z. Yang BS, Engie Salama PharmD, Kourosh Parivar MPharm, Diane D. Wang PhD
Discordance Between Child-Pugh and National Cancer Institute Classifications for Hepatic Dysfunction: Implications on Dosing Recommendations for Oncology Compounds
FDA, hepatic dysfunction, child-pugh, national cancer institute, dosing, oncology compounds
The FDA and European Medicines Agency recommend using Child-Pugh classification for pharmacokinetic evaluation in noncancer subjects with hepatic impairment (HI). Dosing recommendations for oncology compounds for patients with HI are commonly based on Child-Pugh classification. In oncology …
Jul 20th • 18 mins read