Results for 'biopsies'
Ruben Van Paemel, Roos Vlug, Katleen De Preter, Nadine Van Roy, Frank Speleman, Leen Willems, Tim Lammens, Geneviève Laureys, Gudrun Schleiermacher, Godelieve A. M. Tytgat, Kathy Astrahantseff, Hedwig Deubzer, Bram De Wilde
The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children: a review
Liquid biopsies, Pediatric solid tumors, Cell-free DNA profiling
Cell-free DNA profiling via blood samples is emerging as a non-invasive method for cancer genomic characterization. Liquid biopsies are set to be integrated into pediatric cancer clinical trials, offering benefits such as earlier therapy response monitoring and detection of residual disease.…
Jan 3rd • 10 mins read
Sarah M. Dermody, Andrew G. Shuman
Implications of Research Biopsies in Clinical Trials
biopsies, clinical trials, oncology
Increased interest in noninvasive testing for treatment monitoring, tumor burden estimation, and disease recurrence prediction. Lower-risk research specimens and liquid biopsies (blood, saliva, urine) offer alternatives to invasive biopsies. Liquid biopsies present new privacy and risk considera…
Aug 31st • 2 mins read
Jonathan H. Cheng, Justin W. Tiulim, Sheng Zhou, Anthony El-Khoueiry and Jorge Nieva
Mandatory Research Biopsy Requirements Delay Initiation of Clinical Trials
biomarker, clinical trial, targeted therapy, immunotherapy, mandatory research biopsy, oncology, lung cancer, head and neck cancer
The study investigates the impact of requiring fresh tumor tissue biopsies for enrollment in clinical trials. Key findings include: Requiring biopsies significantly increases screening duration, with a median of 30 days compared to 14 days for trials without biopsy requirements (p < 0.0001). …
Oct 18th • 10 mins read