Towards a novel approach guiding the decision-making process for anticancer treatment in patients with advanced cancer: framework for systemic anticancer treatment with palliative intent

Patient-centered cancer care, Advanced cancer decision-making, Stepwise decisional process, Palliative care domains, Illness understanding in oncology, Symptom control in cancer, End-of-life preparation, Patient-physician interaction, SACT-PI Decision Fra

Patient-centered decisions in advanced cancer care demand a step-wise decisional process, not a single decision act. The decision process includes key palliative care domains, e.g. illness understanding, symptom control, or end-of-life preparation. Patients' attitudes, beliefs, hopes, patient-ph…

Jun 1^st • 25 mins read

An Overview of Cancer Drugs Approved by the US Food and Drug Administration Based on the Surrogate End Point of Response Rate

FDA, RR, drug approvels, OS

Many cancer drugs come to market based on single-arm studies with modest RRs. Most of these drugs are tested in studies of over 100 patients prior to approval. Most (60%) of these approvals lack randomized clinical trials during the life cycle of the product. Our findings suggest greater room for th…

May 28^th • 5 mins read

Outcome measures for oncology alternative payment models: practical considerations and recommendations

Oncology, payment, models

This paper focuses on synthesizing existing research on quality measures in oncology, particularly outcome-based quality measures which are underutilized. A set of "core outcome measures" is proposed for future oncology alternative payment models (APM). The study design includes a literature rev…

Dec 1^st • 10 mins read